Sleep Loss & Inflammation
Acute sleep deprivation has been proven to modify inflammatory mediators in controlled, experimental research on humans.
Elevations in these mediators have been observed in healthy, well vetted subjects who underwent experimental vigils lasting longer than 24 hours.
They have also been observed in response to varying sleep lengths limited to 25–50% of the recommended 8 hours of sleep per day.
The future onset of metabolic syndrome disease in healthy, asymptomatic persons has been linked to such sub-clinical shifts in baseline inflammatory cytokines, despite the fact that these changed profiles only represent minor modifications.
It is unknown how experimental sleep deprivation in humans alters the inflammatory status, but it is believed that autonomic activation and metabolic alterations are important contributors.
Role of sleep deprivation in immune-related disease risk and outcomes
Regularly limiting sleep may damage immune stem cells, thereby raising the risk of inflammatory diseases and heart disease, according to a tiny new study.
According to a report published on Wednesday in the Journal of Experimental Medicine, an analysis of blood samples from 14 healthy volunteers who agreed to have their sleep reduced by 112 hours every night for six weeks revealed long-term changes in the way these stem cells behaved, resulting in a proliferation of the white blood cells that can cause inflammation.
The main takeaway from this research, according to study co-author Filip Swirski, head of the Cardiovascular Research Institute at Icahn Mount Sinai in New York, is that sleep reduces inflammation and sleep loss raises inflammation. “Immune cells circulated in the blood at higher levels in participants who experienced sleep restriction. These cells are important contributors to inflammation.
He noted that while some degree of inflammation is necessary to combat infections and repair wounds, going overboard can be dangerous. He said that chronic, excessive inflammation has been connected to Alzheimer’s and neurodegenerative illnesses like heart disease.
Sleep Deprivation May Increase Risk for Systemic Lupus in Women
Wednesday, September 20, 2022 The HealthDay News An online study from Arthritis Care & Research on September 12 found that a lack of sleep raises the risk of systemic lupus erythematosus (SLE), particularly in women who also have depression or physical discomfort.
Boston’s Brigham and Women’s Hospital’s May Y. Choi, M.D., and colleagues investigated if a lack of sleep increased the likelihood of getting SLE. Data from 186,072 female participants in the Nurses’ Health Study (NHS; 1986 to 2016) and NHSII were used in the analysis (1989 to 2017).
The researchers discovered that chronic low sleep duration (no more than five hours per night as opposed to more than seven to eight hours per night) was linked to an increased risk of SLE (adjusted hazard ratio [HR],2.47), which persisted in a four-year lagged analysis (adjusted HR,3.14) as well as after adjusting for shift work, physical pain, and depression (adjusted HR, 2.13).
Just one hour of extra sleep each night can lead to better eating habits
Do you want to change your diet? Consider improving your sleep.
Researchers have recently shown that our sleep patterns have a significant impact on the quantity and types of food we eat as well as whether we gain or lose body fat. Losing sleep can lead to hormonal and cognitive changes that increase food cravings and increase calorie intake, particularly from processed meals high in fat and sugar.
If you’re one of the millions of adults who suffer from chronic sleep deprivation, research indicates that even one hour more of sleep per night can improve your eating patterns and possibly even help you lose weight.
Many people struggle to get a decent night’s sleep. According to sleep specialists, the typical adult needs at least seven hours of sleep per night. However, at least one in three adults often misses out on adequate sleep. Some individuals don’t get enough sleep so they may remain up late working or browsing the internet. Numerous adults, including millions of people, experience sleep disorders such persistent insomnia, sleep apnea, or restless legs syndrome.
It’s imperative to comprehend the variables that influence your everyday dietary choices if you want to improve your general health. Eating Lab will investigate the different biological and cultural factors that affect our eating patterns every Tuesday. Many studies now indicate that a significant factor is how well you sleep at night.
